The US government reported that job creation ground to a virtual halt last month
Bourses in Europe and Asia finished solidly lower. Wall Street also retreated, although an afternoon rally kept losses to a minimum. The broad-based S&P 500 finished down 0.2 percent.
US employers added just 20,000 net new positions in February, collapsing from a blockbuster gain of 311,000 in January and far below the 173,000 economists had projected, according to a US Labor Department report.
CMC Markets analyst Michael Hewson said the paltry headline jobs number was offset by higher wages and a drop in unemployment to 3.8 percent from 4.0 percent.
But Hewson added "the recent rally in global equity markets appears to have run out of steam as investors start to take profits over concerns that the macro economic backdrop is much weaker than was thought."
- 'Selloff continues apace' -
Asia's markets suffered sharp losses after China revealed exports plunged more than 20 percent in February, while imports also fell sharply -- both badly missing expectations.
"The stock market selloff has continued apace today, with a sharp drop in Chinese exports leading to further weakness across the board," said IG analyst Joshua Mahony.
London's FTSE 100 index closed down 0.7 percent, while Frankfurt fell 0.5 percent and Paris shed 0.7 percent, extending Thursday's ECB-fueled losses.
The euro managed to rebounded slightly after hitting a near two-year low after the ECB news on Thursday
The ECB said eurozone interest rates would be stuck around historic lows until the year's end at best, with central bank chief Mario Draghi warning the region was "coming out of, and maybe we still are in a period of continued weakness and pervasive uncertainty."
British Prime Minister Theresa May will try to get her divorce deal from the European Union over the line in the vote on Tuesday, just two and half weeks before the UK is set to exit the European Union.
The pound fell against both the euro and the dollar.
- Key figures at 2140 GMT -
New York - Dow: DOWN 0.1 percent at 25,450.24 (close)
New York - S&P 500: DOWN 0.2 percent at 2,743.05 (close)
New York - Nasdaq: DOWN 0.2 percent at 7,408.14 (close)
London - FTSE 100: DOWN 0.7 percent at 7,104.31 (close)
Frankfurt - DAX 30: DOWN 0.5 percent at 11,457.84 (close)
Paris - CAC 40: DOWN 0.7 percent at 5,231.22 (close)
EURO STOXX 50: DOWN 0.8 percent at 3,283.60 (close)
Tokyo - Nikkei 225: DOWN 2.0 percent at 21,025.56 (close)
Hong Kong - Hang Seng: DOWN 1.9 percent at 28,228.42 (close)
Shanghai - Composite: DOWN 4.4 percent at 2,969.86 (close)
Euro/dollar: UP at $1.1233 from $1.1193 at 2200 GMT
Dollar/yen: DOWN at 111.15 yen from 111.58 yen
Pound/dollar: DOWN at $1.3016 from $1.3085
Euro/pound: UP at 86.30 pence from 85.55 pence
Oil - Brent Crude: DOWN 56 cents at $65.74 per barrel
Oil - West Texas Intermediate: DOWN 59 cents at $56.07 per barrel
